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Individual solutions for the life science industry are part of our DNA

Even in highly sensitive production processes such as gene analysis, DNA analysis or oligosynthesis, precision is no longer the only thing that matters. Speed, productivity and reproducibility with increasingly sophisticated and complex methods are the decisive criteria for making reliable investigation possible.

 

We are familiar with these parameters and design our components and systems with the appropriate parameters: sophisticated fluidics technology for laboratories, resistance to the highest chemical loads, real-time monitoring for quality control, optimisation of process flows and, last but not least, highly individual solutions. As an experienced solution provider with numerous proven products for the Life science industry, we are able to respond to your specific requirements with the precision of chromatography.

We supply everything from a single source, from individual valves and sensors for regulation, measurement and control technology to the finished dosing application, including the approval documents and documentation. This is how we ensure that all Bürkert components in the critical processes of the Life science industry work together in a precisely coordinated manner and at the same time support your supply chain. This makes Bürkert the perfect partner for all applications in the laboratory, in research and at the point of care.

Specific devices for specific processes in the Life science industry

We also analyse processes – because as fluidics experts we develop solutions for your device from the tailor-made component to the individually tailored system – you can find out more in a non-binding consultation.

Mixing/dosing in analytical chromatography
The requirement: Exact, reproducible gradient mixtures even with large temperature fluctuations.
The Bürkert solution: Valves with switching accuracy and durability specifically designed for the laboratory environment.
Dosing in the DNA synthesiser
The requirement: Purity and process speed in microdosing.
The Bürkert solution: Our dosing valves offer the decisive properties – highly resistant to aggressive solvents, constant flow and switching behaviour, maximum service life values for media-separated valves and digital communication interfaces for process or function monitoring in real time.
Flow control and waste handling in the DNA synthesiser
The requirement: The flow rate in the vacuum influences the rate of oligo growth and therefore also the quality and purity of the oligos. At the same time, the excess reagents are disposed of.
The Bürkert solution: Our valve systems ensure precise vacuum control within an environment that is highly flammable due to solvents.
Dosing in the PCR device
The requirement: Exclude cross-contamination with strong cleaning agents.
The Bürkert solution: Microfluidic valves with excellent chemical resistance and being able to be rinsed, enable safe dosing. In addition, the real-time monitoring of the dosing valve components using process monitoring and functional diagnostics ensures efficient processes.
Syringe pump control in the PCR
The requirement: Fast and precise switching operations of the pilot valves for precise dosing.
The Bürkert solution: Our 3/2-way valves offer a wide selection for every flow range. Thanks to the integrated function diagnosis any malfunctions are detected immediately. With a complete syringe pump head, Bürkert also offers application solutions with integrated process monitoring.
Syringe pump control in the NGS
The requirement: Fast and precise switching operations of the pilot valves for precise dosing.
The Bürkert solution: Our 3/2-way valves offer a wide selection for every flow range. Thanks to the integrated function diagnosis, malfunctions are detected immediately. With a complete syringe pump head, Bürkert also offers application solutions with integrated process monitoring.
Dosing in the NGS
The requirement: Cross-contamination of different samples must be prevented under all circumstances.
The Bürkert solution: Our dosing system aspirates and dispenses reagents without contact and can also do without conventional single-use components for waste disposal.
Gas and liquid dosing in the laboratory bioreactor
The requirement: When cultivating cells in the bioreactor, the smallest deviations or contamination lead to the destruction of the cell culture or the reproduction of the wrong cells.
The Bürkert solution: Our components and systems ensure safe gas and liquid dosing thanks to precise switching, a long service life and excellent rinsing ability.

Bürkert Systemhaus – always open to your requirements

As an engineer you know that: Elaborate and viable results are complex and take time. Use the know-how of our specialists to act more efficiently. We listen, analyse and develop future-oriented products and customer-specific application solutions until they are ready for series production. You and your projects are always welcome in the Systemhaus – on site, by telephone or virtually.

Genomic devices – our highlights for a wide variety of applications

Type 6650

2/2-way Flipper-Solenoid Valve with separating diaphragm

Type 6650
  • Only 4.5 mm wide
  • Medium isolation, for aggressive fluids
  • Direct-acting
  • Vacuum up to 7 bar
  • Short response times

Type 6724

2/2 or 3/2-way Whisper Valve with media separation

Type 6724
  • Highest chemical resistance
  • Compact design with 8.9 mm installation width
  • DN 0.8 mm (vacuum up to 5 bar) and 1.2 mm (vacuum up to 3 bar)
  • Very fast, almost silent switching with < 20 dB (A) and very low power consumption
  • High back-pressure tightness, excellent cleanability and 100% duty cycle

Type 8763

Pressure controller for precise time-pressure dosing

Type 8763
  • Repeatable and accurate dosing of liquids in the µl range
  • Response time in milliseconds and active pressure relief for optimum control performance
  • Digital communication for easy integration into your fieldbus network
  • Extended functionality through additional sensor input and actuator output e.g. for pump or additional pressure sensor
  • Active vent valve to minimize consumption of costly carrier gas

Useful information for fluid technology in gene analysis

Read our application notes and white papers to learn more about our technologies – or speak directly to our genomics instrument experts.

Oligonucleotide synthesis: valves and block solutions for exact dosing in oligo synthesizers

There is growing demand for synthetic DNA for use in research. One method of producing these types of artificial DNA strands is oligonucleotide synthesis. This process requires exact dosing of up to twelve different liquids in the microlitre (μl) range. The purity of an oligo is primarily determined by its full length and the correct order of bases. This dosing process used in the production of oligonucleotides places high demands on the synthesizers: In addition to the purity of the oligos, a high process speed is required in order to make the process economical.How can you ensure the controlled and reliable production of high-quality DNA strands? Read on to discover how valves and valve systems from Bürkert can help you dose faster and more efficiently.

How innovative dosing systems make liquid chromatography more accurate

As a user of a chromatography device, you know: Only if substances from the pharmaceutical or clinical environment or from the environment and forensics can be analysed exactly and quickly in the chromatograph can you work really efficiently and ensure fast further processing. The precision in the dosage also determines how well you can automate your processes.

Reliable analytical devices with ValveInsight diagnostics

The operation of devices in analytical and medical technology must be monitored, as malfunctions may have serious consequences. With ValveInsight valve diagnostics, you can monitor valves with electrodynamic actuators.

Precise and efficient dosing with Bürkert for high synthesis quality

Learn more about the advantages of precise dosing in oligosynthesizers or ask us directly for an individual specification for your devices.